Sinclair Method Studies
Published on: 11/06/2025
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
The Sinclair Method (TSM) offers a compassionate, scientifically-backed alternative to traditional abstinence-based approaches for treating Alcohol Use Disorder (AUD). By utilising the opioid antagonist naltrexone, TSM enables individuals to gradually reduce their alcohol consumption, leading to significant benefits both physically and emotionally.